Webb1 sep. 2024 · 此外HIOEC细胞形态由椭圆形变成纺锤形;从TEM结果显示,EV处理后的上皮细胞中核质内陷,出现多个核仁,此为口腔癌前病变的典型特征。 表明OSCC-EV增强了HIOEC的EMT,促进其发生癌前转化。 4. miR-let-7c/p53/PTEN通路参与了正常上皮细胞的癌前转化 OSCC-EV下调了HIOEC细胞中p53和PTEN的蛋白质水平,由于EV可通过传 … WebbA Knockdown of ALKBH5 and FTO using siRNA in HIOEC cells. B Knockdown of ALKBH5 and FTO increased m6A modification of RNA in HIOEC cells. C Knockdown of ALKBH5 and FTO activated the STING signaling pathway in HIOEC cells. D Knockdown of ALKBH5 and FTO increased mRNA expression levels of IFNα, IFNβ, ISG15 and CXCL10 in …
The effects of LPS pretreatment on the cisplatin-induced
Webb摘要: 目的诱导永生化口腔上皮细胞系(hioec)细胞恶性转化,建立口腔黏膜上皮细胞体外癌变模型.方法通过化学致癌剂苯并芘[b(a)p]体外诱导hioec细胞,逐步筛选到鳞状细胞癌细胞系hioec-b(a)p.通过微分干涉显微镜和he染色观察细胞形态学改变;用软琼脂集落形成及裸小鼠异体皮下成瘤的实验鉴定hioec-b(a)p ... WebbHIOEC and OSCC cell lines (5 × 105 ml-1) were pretreated with or without 1 μg/ml LPS for 4 h, then stimulated with 1 μg/ml cisplatin for 24 h. The cells were stained with Annexin V and PI and... definition of special ed
[Effect of HPV 16 E5 on E6 and E7 gene induced human ... - PubMed
Webb1 maj 2008 · The human immortalized oral epithelial cells (HIOECs), which had been obtained from normal oral mucosa immortalized by transfection of HPV16 E6/E7 gene as previously described, 8 were cultured with defined keratinocyte medium-SFM (Gibco, USA), and treated intermittently and gradually with 0.1–1.2 μg/ml benzo (a)pyrene [B … http://www.kqswyx.cn/CN/abstract/abstract7568.shtml Webb14 nov. 2024 · Abbreviations: HIOEC, human immortalized oral epithelial cell; OSCC, oral squamous cell carcinoma. Display full size FAM46C overexpression in OSCC cells To test the function of FAM46C in regulating the proliferation and apoptosis of OSCC cells, we overexpressed FAM46C in OSCC cells. definition of special tooling