Web1 feb. 2024 · The analysis of Ldb2 single-mutant mice reveals a compensatory role of Ldb1 for Ldb2 during corticospinal motor neuron (CSMN) differentiation. Animals lacking both Ldb1 and Ldb2 uncover the requirement for Ldb2 during CSMN differentiation, manifested as incomplete CSMN differentiation, and ultimately leading to a failure of the … Webldb2 PATHOLOGY LIVER CANCER BREAST CANCER CARCINOID CERVICAL CANCER COLORECTAL CANCER ENDOMETRIAL CANCER GLIOMA HEAD AND NECK …
Identification of key tumor stroma-associated …
WebAssigned HPA protein class (es) for the encoded protein (s). Number of protein-coding transcripts from the gene as defined by Ensembl. A summary of the overall protein … In breast cancer reactive stroma, ITM2A downregulation is associated with shorter survival of patients . Matrix-producing stromal LDB2 has prognostic value in breast cancer . Among the downregulated genes in BTS, many have been associated with breast cancer onset, invasion, progression, and metastasis … Meer weergeven We identified 1058 DEGs between BTS and normal stroma. Among these DEGs, 782 were upregulated (Supplementary Table S4) and 276 were downregulated (Supplementary Table S5) in BTS. The top 25 … Meer weergeven To identify the hub genes of the DEGs in BTS, we input all the DEGs into the STRING tool [28]. We identified 233 hub genes (degree ≥ 25), including 194 upregulated and 39 downregulated genes in BTS … Meer weergeven The eXpression2Kinases algorithm identified 20 upstream TFs playing a significant regulatory role toward the DEGs (Supplementary Table S8). These TFs included IRF8, NFE2L2, TP63, RUNX1, … Meer weergeven We further analyzed the expression of the stromal prognostic upregulated and downregulated genes in the TCGA breast invasive carcinoma (BRCA) cohort. Interestingly, … Meer weergeven onsite covid-19 ag self test buy australia
LDB2 inhibits proliferation and migration in liver cancer cells by ...
Web21 mrt. 2024 · LDB2 (LIM Domain Binding 2) is a Protein Coding gene. Diseases associated with LDB2 include Retinal Detachment and Acute Erythroid Leukemia. … WebLDB2 belongs to the LIM-domain binding family and functions as an adaptor for transcriptional regulation. Here we found that LDB2 is downregulated in HCC samples. LDB2 has the ability to... Web3 mrt. 2024 · The relationship between LDB2 and the prognosis of patients with lung adenocarcinoma was analyzed using GEPIA and GEO databases. We further analyzed the role of LDB2 in regulating cell behaviors in a H1299 cell model over-expressing LDB2 using cell counting, soft agar colony forming assay and flow cytometry. ioctls in linux