Thioredoxin domain-containing protein
WebThioredoxin domain containing 5 (TXNDC5), an ER-localized protein disulfide isomerase, was shown to facilitate ECM protein folding and to contribute to the stability of ECM … WebTXNDC17 encodes a 14-kD protein that has a thioredoxin (TRX, or TXN; 187700) fold and a TRX-like active-site sequence. TXNDC17 and TRX function in reducing protein disulfide …
Thioredoxin domain-containing protein
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WebApr 28, 2014 · Thioredoxin-related protein of 14 kDa (TRP14, also called TXNDC17 for thioredoxin domain containing 17, or TXNL5 for thioredoxin-like 5) is an evolutionarily well-conserved member of the thioredoxin (Trx)-fold protein family that lacks activity with classical Trx1 substrates. WebThe thioredoxin (TXN) system and TXN-domain-containing protein (TXNDC) family form networks maintaining the cellular reducing environment. Recently, the importance of these genes in the tumor environment has been emphasized. Aim: To investigate the clinical significance of TXNs and TXNDC family members in HCC.
Thioredoxins are small disulfide-containing redox proteins that have been found in all the kingdoms of living organisms. Thioredoxin serves as a general protein disulfide oxidoreductase. It interacts with a broad range of proteins by a redox mechanism based on reversible oxidation of 2 cysteine thiol groups to a disulfide, accompanied by the transfer of 2 electrons and 2 protons. The net result is the covalent interconversion of a disulfide and a dithiol. Web2. TXNIP. Thioredoxin-interacting protein (TXNIP), also known as vitamin D upregulated protein-1 (VDUP-1) or thioredoxin-binding protein-2 (TBP-2), is a multifunctional protein that is essential for many cellular processes such as metabolic activities, growth, division, and cell death [].It was initially believed that TXNIP was restricted only to the cytoplasm.
WebGene ID: 128368198, updated on 28-Feb-2024. Summary Other designations. thioredoxin domain-containing protein 9 WebThe thioredoxin (TXN) system and TXN-domain-containing protein (TXNDC) family form networks maintaining the cellular reducing environment. Recently, the importance of …
WebSep 19, 2024 · Several blood and plasma proteins contain allosteric disulfide bonds which have been implicated in thrombus formation and homeostasis [11,12]. ... such as PDI, ERp5 and ERp57, contain thioredoxin-like domains, it is possible that they are also inhibited. Similar effects were observed by Lawrence et al. ...
WebThioredoxin protein has two cysteine residues in its active site that is a part of antioxidant system.. Thioredoxin system consists of Trx protein, thioredoxin reductase, NADPH coenzyme, and thioredoxin-interacting protein. • Trx system also plays a role in various biological functions such as regulation of apoptosis, redox regulation of transcription … honorific language meaningWebRelevant books, articles, theses on the topic 'Thioredoxin domain containing protein 5.' Scholarly sources with full text pdf download. Related research topic ideas. honorific in lisbonWebJun 1, 2001 · Thioredoxin domain-containing protein 17. Alternative names. 14 kDa thioredoxin-related protein (TRP14) Protein 42-9-9; Thioredoxin-like protein 5; Gene … honorific ltdWebTXNDC15, C5orf14, Thioredoxin domain-containing protein 15. Close. Applications. Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications have not been tested. Recommended Dilution. Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:10-1:50 Optimal dilutions to be determined by the researcher. honorific listWebMar 29, 2024 · Overactivated osteoclasts lead to many bone diseases, including osteoporosis and rheumatoid arthritis. The p38 MAPK (p38) is an essential regulator of … honorificityWebRegulated reversal of cysteine oxidation is dependent on activities of the conserved superfamily of Thioredoxin (TRX) enzymes that function as cysteine reductases. The plant immune system recruits specific TRX enzymes that have the potential to functionally regulate numerous immune signalling proteins. honorific mayorhonorific of india